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. 2021 Aug 25;237(1):239–257. doi: 10.1002/jcp.30562

Figure 5.

Figure 5

Schematic drawing of neural niches and their main components. Top: Neural stem cell (NSC) niche in the subventricular zone of the lateral ventricle (SVZ); located underneath ependymal cells, NSCs produce transit‐amplifying (TA) progenitors that are able to differentiate into the three main nervous cell types: neurons, astrocytes, and oligodendrocytes. Bottom: Neural stem cells in the subgranular zone of the hippocampus (SGZ) reside at the interface between the hilus and the granule cell layer of the dentate gyrus; in this niche, NSCs give rise to neurons through intermediate precursors that migrate toward the granule cell layer and become mature neurons. CSF, cerebrospinal fluid