TABLE 1.
N source | Initial concn (g liter−1) | Residual concn (g liter−1) | Residual glucose concn (g liter−1) | Lovastatin production (mg liter−1) |
---|---|---|---|---|
Di-ammonium tartrate | 13.7 | —b | 0 | <1 |
Ammonium nitrate | 4 | — | 0 | <1 |
Ammonium acetate | 11 | — | 2.5 | <1 |
Sodium nitrate | 4 | — | 0 | <1 |
Urea | 4.5 | — | 0 | <1 |
Sodium glutamate | 7 | 0.1 | 0 | 25 |
Sodium glutamate | 12.5 | 0.4 | 0 | 47 |
Sodium glutamate | 18 | 6.5 | 0 | 39 |
Histidine | 12.5 | 6.0 | 0 | 46 |
Glycine | 12.5 | 0.0 | 0 | 17 |
Arginine | 12.5 | 7.0 | 0 | 1.5 |
Isoleucine | 12.5 | 2.0 | 0 | <1 |
After cultivation for 140 h in shake flask in chemically defined medium with glucose (45 g liter−1).
—, not measured.