Central Illustration.

Main Phenotypic Differences Between Fulminant COVID-19–Related Myocarditis With and Without Multisystem Inflammatory Syndrome in Adults

MIS-A⁺ and MIS-A⁻ fulminant COVID-19–related myocarditis patients have 2 distinct phenotypes with different clinical presentations, prognosis and immunological profiles. For box and whisker plots: the center line denotes the median value (50th percentile), whereas the box contains the 25th to 75th percentiles of dataset. The whiskers mark the 5th and 95th percentiles. ICU = intensive care unit; MIS-A = multisystem inflammatory syndrome in adults; RT-PCR = reverse transcription polymerase chain reaction; U.S.-CDC = U.S. Centers for Disease Control and Protection.