Table 1.
Patient baseline characteristics.
| Normal values | MSC group (n=8) | Matched control group | n | p 1 | Whole control cohort | n | p2 | |
|---|---|---|---|---|---|---|---|---|
| Age (years) | – | 50 (43-58) | 54 (49.5-63) | 24 | 0.089 | 67 (58-73) | 247 | 0.0016 |
| BMI (kg/m²) | – | 31.5 (26.5-35.4) | 30.1 (24.1-32.8) | 19 | 0.34 | 28.7 (25. 7-31.8) | 227 | 0.25 |
| PaO2/FiO2 | – | 85.5 (77.9- 93.4) | 86.5 (60.6-102.9) | 24 | 0.89 | 76.6 (64.0-102.9) | 242 | 0.33 |
| Lymphocyte count (x109/L) | 1.10-3.70 | 0.82 (0.59-0.88) | 0.77 (0.49-1.06) | 24 | 0.90 | 0.63 (0.41-0.90) | 247 | 0.34 |
| SOFA score | – | 4 (3-5) | 4 (3-5) | 24 | 0.81 | 4 (3-6) | 182 | 0.54 |
| CRP (mg/L) | < 5.0 | 171.6 (127.5- 212.2) | 126.5 (62.2-216.5) | 24 | 0.54 | 119.4 (63.3- 197.1) | 247 | 0.31 |
| Ferritin (µg/L) | 22-275 | 1434.4 (756.4-2742.4) | 1962.6 (990.1-2875.1) | 24 | 0.78 | 1523.5 (740.5- 2677.7) | 132 | 0.97 |
| D-dimers (µg/L) | < 500 | 679.0 (501.5-1713.0) | 1641.5 (628.5-1641.5) | 24 | 0.098 | 1047.5 (599.0- 2043.0) | 206 | 0.38 |
| Creatinine (mg/dL) | 0.55-1.18 | 0.83 (0.47- 1.15) | 0.84 (0.72-1.03) | 24 | 0.39 | 0.85 (0.67- 1.15) | 247 | 0.37 |
| Viral load (cycle threshold) | – | 28.63 (24.05-29.90) | 28.29 (20.68-32.11) | 12 | 0.90 | 25.34 (20.83-29.09) | 139 | 0.26 |
Values are expressed as median (P25-P75). p1 refers to comparisons between the MSC and matched control groups, whereas p2 refers to comparisons between the MSC group and the whole control cohort. BMI, body mass index; SOFA, Sepsis-related Organ Failure Assessment; CRP, C-Reactive Protein.