Table 2.
Clinical and biological outcomes.
| MSC group (n=8) | Matched control group (n=24) | p 1 | Whole control cohort (n=247) | p2 | |
|---|---|---|---|---|---|
| 28-d mortality | 0 (0%) | 5 (20.8%) | 0.025 | 65 (26.3%) | 0.21 |
| 60-d mortality | 0 (0%) | 7 (29.2%) | 0.0082 | 79 (32.0%) | 0.061 |
| ICU-free days | 14 (7-22) | 19 (0-24) | 0.92 | 13 (0-23) | 0.64 |
| Need for MV | 3 (37.5%) | 11 (45.8%) | 0.56 | 109 (44.1%) | 1.00 |
| Invasive ventilation-free days | 11 (0-23) | 0 (0-25) | 0.50 | 0 (0-17) | 0.54 |
| HFNO support-free days | 22 (11-27) | 19 (0-25) | 0.12 | 16 (0-24) | 0.13 |
| O2 support-free days | 19 (9-25) | 18 (0-25) | 0.38 | 15 (0-24) | 0.35 |
| Need for noradrenaline | 2 (25.0%) | 11 (45.8%) | 0.13 | 97 (39.3%) | 0.49 |
| Day-7 CRP (mg/L) | 33.2 (6.3-59.8) | 20.8 (10.6-92.1) | 0.25 | 35.8 (12.2-94.5) | 0.36 |
| Day-7 D-dimers (µg/L) | 821.0 (362.0-1,305.0) | 3,553.0 (1,155.0-6,433.5) | 0.0085 | 1,315.0 (675.0-3,425.0) | 0.14 |
Values are expressed as median (P25-P75) for quantitative parameters and number (frequencies) for qualitative parameters. p1 refers to comparisons between the MSC and matched control groups, whereas p2 refers to comparisons between the MSC group and the whole control cohort. ICU, intensive care unit; MV, mechanical ventilation; HFNO, high flow nasal oxygen.