Table 2.

Hemodynamic variables and MSNA during Oxford procedure

	Pre-RMHE	Post-RMHE	Post-1wk	P
MAP, mmHg
Base	94 ± 2	94 ± 2	93 ± 3	0.995
SNP	84 ± 3*	81 ± 3*	83 ± 3*	<0.001
PE	98 ± 2^	98 ± 1^*	97 ± 3^	0.321
HR, beats/min
Base	61 ± 2	59 ± 3	58 ± 2	0.296
SNP	70 ± 2*	65 ± 2*	65 ± 3*	<0.001
PE	59 ± 3^*	56 ± 3^	54 ± 2^*	0.651
MSNA BR, bursts/min
Base	31.5 ± 2.4	25.2 ± 1.8	26.2 ± 1.9	0.001
SNP	40.3 ± 3.3*	35.0 ± 1.9*	35.9 ± 4.3*	<0.001
PE	28.0 ± 2.5^	21.0 ± 2.4^#	21.4 ± 4.2^	0.932

BR, burst rate; HR, heart rate; MAP, mean arterial pressure; MSNA, muscle sympathetic nerve activity; PE, mean values from 60 to 120 s after phenylephrine HCl; RMHE, repeated moderate heat exposure; SNP, mean values from 30 to 90 s after sodium nitroprusside infusion. P: P values for the factors in two-way repeated-measures ANOVA (up to down): visit (i.e., effects of RMHE), drug, interaction. Subject number: n = 7 for Pre and Post, n = 6 for Post-1wk.

Post hoc: *P < 0.05 vs. base within visit; ^P < 0.05 vs. SNP within visit; #P = 0.042 vs. Pre-RMHE between visits.