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. 2022 Jun 23;133(1):234–245. doi: 10.1152/japplphysiol.00684.2021

Table 4.

Hemodynamic variables and MSNA during cold pressor test

Pre-RMHE Post-RMHE Post-1wk P
MAP, mmHg
 Base 96 ± 2 96 ± 2 97 ± 2 0.501
 CPT 117 ± 4* 120 ± 4* 117 ± 3* <0.001
0.544
HR, beats/min
 Base 64 ± 2 57 ± 2a 60 ± 2 <0.001
 CPT 70 ± 2* 66 ± 3 67 ± 2* 0.006
0.551
MSNA BR, bursts/min
 Base 29.0 ± 2.1 23.9 ± 3.1 25.6 ± 2.8 0.026
 CPT 49.0 ± 4.2* 41.6 ± 4.4*b 41.7 ± 3.2*c <0.001
0.273
MSNA BI, bursts/100 beats
 Base 45.2 ± 2.9 42.4 ± 5.6 42.6 ± 4.8 0.449
 CPT 70.3 ± 6.0* 64.1 ± 7.9* 63.6 ± 6.2* <0.001
0.402

BI, burst incidence; BR, burst rate; CPT, cold pressor test; HR, heart rate; MAP, mean arterial pressure; MSNA, muscle sympathetic nerve activity; RMHE, repeated moderate heat exposure. P: P values for the factors in two-way repeated measures ANOVA (up to down): Visit (i.e., effects of RMHE), stress (i.e., CPT), Interaction. Subject number: n = 9 for Pre, n = 8 for Post and Post-1wk.

Post hoc: within visit *P < 0.05 vs. Base. Between visits: vs. Pre-RMHE, aP = 0.003; bP = 0.015; cP = 0.018.