Figure 1.

Study design. Consort diagram for patient selection (A) as well as case‐control matching workflow (B) are presented. BNP, B‐type natriuretic peptide; DBP, diastolic blood pressure; EF, ejection fraction; eGFR, estimated glomerular filtration rate; HF, heart failure; HFmrEF, heart failure with mid‐range ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; ICU, intensive care unit; NT‐proBNP, N‐terminal prohormone of pro‐B‐type natriuretic peptide; QC, quality control; SBP, systolic blood pressure. *When performing case‐control matching for each HF subtype, only controls (n = 773) that were matched in the comparison of all patients with HF (n = 773) were considered. ^†When matching controls for patients with HFmrEF (n = 144), controls that have been matched to HFrEF (n = 442) were not considered. ^‡ When matching controls to patients with HFpEF (n = 187), controls that were matched in previous comparisons were excluded.