Figure 5.

Transcriptional profiling of WT andLcn2 ^−/−mice muscles. RNA was extracted from (a–c) 3‐ or (d–f) 12‐month‐old WT and Lcn2 ^−/− mice muscles. One μg of total RNA was reverse‐transcribed into cDNA and used for transcriptional analyses. (a, d) Diaphragm, (b, e) quadriceps and (c, f) soleus. The genes analysed are indicated in the abscissa. N = 5–10. Student's t test or Mann–Whitney test. *p < .05; **p < .01 vs WT. cDNA, complmentary DNA; IL6, interleukin‐6; mRNA, messenger RNA; WT, wild‐type