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. 2021 Sep 7;28(12):4194–4203. doi: 10.1111/ene.15075

TABLE 3.

Sustained and delayed response to erenumab in patients who continued with erenumab 70 mg (n = 42) and patients who escalated the dosage to 140 mg (n = 53)

Patients who continued with 70 mg dose Patients escalating dose to 140 mg Total
Average reduction MMD in months 1–3 ≥50% 
N 21 4 25
Sustained responders, n (%) 15 (71) 3 (75) 18 (72)
Average reduction MMD in months 1–3 <50% 
N 21 49 70
Delayed responders, n (%) 5 (24) 11 (22) 16 (23)
Average reduction MMD in months 1–3 ≥30% 
N 35 19 54
Sustained responders, n (%) 31 (89) 17 (89) 48 (89)
Average reduction MMD in months 1–3  <30% 
N 7 34 41
Delayed responders, n (%) 1 (14) 7 (21) 8 (20)

N total = 95 (all patients who completed the 6‐month follow‐up period). Sustained responders = patients who achieved an average of ≥50% or ≥30% reduction in MMD during the first 3 months and during the last 3 months of treatment. Delayed responders = patients who did not achieve an average of ≥50% or ≥30% reduction in MMD during the first 3 months of treatment, but did during the last 3 months of treatment.

Abbreviation: MMD, monthly migraine days.