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Non‐inferiority (NI) tests on the primary and secondary outcomes. Non‐inferiority was claimed if p < 0.021 for urinary NGAL, or p < 0.013 for urinary IL‐18 and AKI, defined by RIFLE categories: Risk, Injury or Failure. HES, Third‐generation hydroxyethyl starch; NGAL, urinary neutrophil gelatinase‐associated lipocalin; IL‐18, urinary interleukin‐18; AKI, acute kidney injury assessed as Risk, Injury or Failure by RIFLE classification based on creatinine values vs. No Risk.
