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. 2022 Jul 14;37(1):1995–2003. doi: 10.1080/14756366.2022.2098954

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — 1,2,3-Triazole-pyridine hybrids were novel FTO inhibitors. (A) The inhibitory activity of compound C6 against FTO; (B) The inhibitory activity of compound C8 against FTO; (C) Expression of FTO in EC109&shFTO and EC109&shControl cells; (D) Cell viability of compound C6 against EC109&shFTO and EC109&shControl cells. FB23-2 as a reported FTO inhibitor was the reference molecule.