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. 2022 Mar 2;46(4):227–235. doi: 10.1080/01658107.2022.2038638

Table 2.

Comparison of the findings of eye movement recordings between amyotrophic lateral sclerosis patients and healthy controls

  ALS patients(n = 62) Healthy controls(n = 85) p value
Median age (years) 60.5 ± 11 45.27 ± 15 .111
Sex ratio (male: female) 1.21 0.83 .098
Percentage of abnormal eye movement recording 72.6% 12.8% .000
Median saccadic latencies ± IQR (ms) 290 ± 37 279 ± 33 .102
Percentage of prolonged latencies 34% 12.9% .002
Percentage of altered horizontal smooth pursuit 56.5% 21.2% .000
Median gain ± IQR 0.54 ± 0.17 0.68 ± 0.17 .004
Median anti-saccadic error rate ± IQR 13 ± 6 3 ± 4 .002
Percentage of altered anti-saccades 24.2% 0 .000

ALS = amyotrophic lateral sclerosis

IQR = interquartile range