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. 2022 Apr 15;21(15):1578–1589. doi: 10.1080/15384101.2022.2057762

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Figure 3. — Exo improved MI induced by SAP through activating Akt/Nrf2/HO-1 signaling pathway. (a) The influence of Exo and LY294002 on morphological changes of myocardial tissues was assessed using HE staining. (b) Sirius Red staining was used to assess collagen deposition. (c) Masson staining was used to assess collagen deposition. (d) The influence of Exo and LY294002 on infarction ratio was analyzed. * P < 0.05 compared with group SAP. # P< 0.05 compared with the group SAP+Exo. 10 rats in each group were used in this study, and the infraction ratio was calculated with at least three independent experiments.