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. 2022 Jun 30;9:951275. doi: 10.3389/fmolb.2022.951275

FIGURE 2.

FIGURE 2

The ferroptosis inducers and inhibitors tested in animal models of AKI, including rhabdomyolysis induced AKI, drug-induced AKI, ischemia-reperfusion induced AKI, and other causes induced AKI. ACSL4, acyl-coenzyme A synthetase long chain family member 4; DFOB, desferrioxamine B; FTH1, ferritin heavy chain 1; Fer-1, ferrostatin-1; FG-4592, roxadustat; FSP1, ferroptosis suppressor protein 1; GPX4, glutathione peroxidase 4; IL-33, interleukin 33; MIOX, myo-inositol oxygenase; PANX1, pannexin1; St-PGA-CL-BDMC, star-shaped polyglutamate conjugate of bisdemethoxycurcumin.