TABLE 1.
Demographics by study group (full analysis set)
| Demographic variable | Normal (n = 10) | Mild (n = 7) | Moderate (n = 8) | Severe (n = 6) | All participants (N = 31) |
|---|---|---|---|---|---|
| Median (range) age, y | 54.5 (43.0–62.0) | 57.0 (52.0–62.0) | 56.5 (45.0–64.0) | 49.0 (44.0–60.0) | 55.0 (43.0–64.0) |
| Sex, n (%) | |||||
| Female | 2 (20.0) | 0 | 2 (25.0) | 1 (16.7) | 5 (16.1) |
| Male | 8 (80.0) | 7 (100) | 6 (75.0) | 5 (83.3) | 26 (83.9) |
| Race, n (%) | |||||
| Caucasian | 6 (60.0) | 4 (57.1) | 7 (87.5) | 6 (100) | 23 (74.2) |
| Black | 4 (40.0) | 2 (28.6) | 1 (12.5) | 0 | 7 (22.6) |
| Other | 0 | 1 (14.3) | 0 | 0 | 1 (3.2) |
| Ethnicity, n (%) | |||||
| Hispanic/Latino | 4 (40.0) | 1 (14.3) | 6 (75.0) | 5 (83.3) | 16 (51.6) |
| Other | 6 (60.0) | 6 (85.7) | 2 (25.0) | 1 (16.7) | 15 (48.4) |
| Median (range) weight, kg | 83.6 (56.3–100.5) | 82.4 (69.4–103.9) | 82.2 (61.1–100.5) | 88.7 (60.4–114.9) | 83.7 (56.3–114.9) |
| Median (range) height, cm | 173.8 (150.5–185.0) | 180.0 (170.0–187.0) | 166.6 (158.0–174.1) | 176.5 (155.0–181.0) | 174.0 (150.5–187.0) |
| Median (range) BMI, kg/m2 | 27.9 (21.5–29.4) | 24.2 (20.8–32.1) | 28.3 (22.2–36.8) | 30.2 (23.6–35.6) | 27.4 (20.8–36.8) |
| Median (range) BSA, m2 | 2.0 (1.6–2.3) | 2.1 (1.8–2.3) | 2.0 (1.7–2.2) | 2.1 (1.7–2.4) | 2.0 (1.6–2.4) |
BMI, body mass index; BSA, body surface area.
BMI (kg/m2) = weight (kg)/height (m)2.
BSA (Gehan and George): BSA (m2) = 234.94 × (height [cm]0.422) × (weight [kg]0.515)/10000.
BMI and BSA were calculated using the baseline weight and baseline height.