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| Vonsattel grading system | JHD brains (N = 50) | AHD brains (N = 1300) |
|---|---|---|
| Grade 0 | Not reported | 1% |
| Grade 1 | 10% a | 4% |
| Grade 2 | Not reported | 16% |
| Grade 3 | 26% | 53% |
| Grade 4 | 64% | 28% |
Ninety percent of grade 1 juvenile‐onset Huntington disease (JHD) brains were from JHD patients who committed suicide and therefore do not reflect end‐stage disease. For the adult‐onset Huntington disease (AHD) brains, these percentages are unknown/not provided.
