. 2021 Oct 13;29(1):286–294. doi: 10.1111/ene.15129

TABLE 1.

Demographic and clinical data in controls and diabetic patients with no, mild and moderate‐to‐severe neuropathic pain

	Controls n = 38	No pain n = 43	Mild pain n = 34	Moderate‐to‐severe pain n = 41	Kruskal–Wallis test
Age (years)	57 (36)	68 (47) ^a	68 (34) ^a	61 (50) ^b	H(2) = 9.19, p = 0.01
Sex (female)	18	11	12	21	0.07 ^c
Type of diabetes (T1DM/T2DM)	0	20/23	5/29	20/21	<0.0001 ^c
Duration of diabetes (years)	0	16 (66)	15 (50)	24 (66) ^b	H(2) = 5.97, p = 0.051
BMI (kg/m²)	26 (24)	29 (35)	32 (45) ^a	29 (18)	H(2) = 4.46, p = 0.1
HbA1c (%)	5.6 (1.3)	7.2 (7.4) ^a	7.4 (4.3) ^a	8.1 (7.3) ^a , ^d	H(2) = 6.03, p = 0.05
IFCC (mmol/mol)	37.35 (20.4)	55 (81.0) ^a	57 (46.0) ^a	65 (79.0) ^a , ^d	H(2) = 5.9, p = 0.05
HDL‐C (mmol/l)	1.53 (1.72)	1.38 (2.32)	1.33 (2.10)	1.44 (2.78)	H(2) = 2.1, p = 0.3
Triglycerides (mmol/l)	1.60 (4.3)	1.10 (2.4) ^a	1.65 (5.0) ^d	1.40 (3.6)	H(2) = 7.6, p = 0.02
LDL‐C (mmol/l)	2.84 (2.7)	1.63 (2.62)	1.97 (3.6) ^a	1.86 (2.9)	H(2) = 2.6, p = 0.2

Kruskal–Wallis test is performed between groups of patients. All data are presented as median (range).

Abbreviations: BMI, body mass index; HDL‐C, high density lipoprotein cholesterol; IFCC, International Federation of Clinical Chemistry; LDL‐C, low density lipoprotein cholesterol; T1DM, type 1 diabetes; T2DM, type 2 diabetes.

^{^a}

Significant difference compared to controls.

^{^b}

Significant difference compared to mild pain.

^{^c}

p value refers to Fisher's exact test.

^{^d}

Significant difference compared to no pain.