Skip to main content
. 2022 Jul 18;17(7):e0270121. doi: 10.1371/journal.pone.0270121

Table 1. Causal model.

Clinical Feature Measure Causes
Injury
Age Age
Motor Control MC, Latent Injury
Selective Motor Control SCALE Motor Control, Age
Dynamic Motor Control DMC Motor Control, Age
Strengtha Strength Injury, Motor Control, Age
Spasticity Spasticity Injury, Age
Contracture Latent
Ankle Dorsiflexion Contractureb AnkleDF Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Knee Extension Contractureb KneeExt Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Hamstrings Contractureb Popliteal Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Hip Extension Contractureb HipExt Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Torsion Latent
Tibial Torsionc TibRot Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Femoral Anteversionc FemRot Strength, Spasticity, Dynamic & Selective voluntary motor control, Age
Gait Pattern GDI Strength, Spasticity, Dynamic & Selective voluntary motor control, Age, Ankle ROM, Knee ROM, Popliteal ROM, Hip ROM, Tibial Torsion, Femoral Anteversion
Gross Motor Function GMFM-66 Strength, Spasticity, Dynamic & Selective voluntary motor control, Age, Ankle ROM, Knee ROM, Popliteal ROM, Hip ROM, Gait Pattern

Features included in the causal model illustrated in Fig 1. Measures here match the Fig 1 variable names. The hypothesized direct causes of each feature are listed.

a. Because we measure strength in an age-adjusted manner, we do not include an explicit causal link in our graphical model used for testing plausibility and determining adjustment sets.

b. Ankle, Knee, Hamstrings, and Hip contractures are influenced by an unmeasured latent variable Contracture so that Contracture → Ankle Dorsiflexion Contracture, Contracture → Knee Extension Contracture, Contracture → Hamstrings Contracture, Contracture → Hip Extension Contracture.

c. Tibial Torsion and Femoral Anteversion are influenced by an unmeasured latent variable Torsion so that T → Tibial Torsion, T → Femoral Anteversion.