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. 2022 Jul 18;17(7):e0270121. doi: 10.1371/journal.pone.0270121

Table 3. Predictive model coefficients.

Variable β SE p Units Range TD Description
Intercept 14.7 4.3 < .01 S NA NA GMFM-66 linear intercept [7]
Age 0.08 0.12 .50 Yr. NA NA Child’s age in decimal years (e.g. 10.4 yrs)
SCALE 2.3 .27 < .01 S 0–10 10 SCALE total limb score bilateral average (0–10) [37]
Walk-DMC 0.24 0.04 < .01 S 22–100+* 100 (10) Dynamic motor control scaled from normal [43]
Strength 4.5 0.85 < .01 S 0–5 5 Multivariate strength scale [35]
Spasticity -0.57 0.38 .13 S 0–5 0 Multivariate spasticity scale [33]
GDI 0.17 0.04 < .01 S 0–100+* 100 (10) Gait deviation index [42]
Ankle Dors. Contracture -0.13 0.05 < .01 Deg. > = 0 0 Limitation in achieving > = 21.3° dorsiflexion with knee extended [3941]
Hip Ext. Contracture -0.17 0.08 .02 Deg. > = 0 0 Limitation in achieving > = neutral hip extension [39, 40]
Knee Ext. Contracture -0.11 0.07 .10 Deg. > = 0 0 Limitation in achieving > = 4.0° knee extension with hip at neutral [3941]
Hamstrings Contracture -0.01 0.02 .54 Deg. > = 0 0 Limitation in achieving > = 25.6° knee extension with hip flexed to 90° (Popliteal Angle) [3941]
Femoral Anteversion -0.01 0.02 .44 Deg. > = 0 0 Difference from typical anteversion (26.9°) [38, 41]
Tibial Torsion -0.08 0.08 .21 Deg. > = 0 0 Non-weightbearing bimalleolar axis difference from typical (16.0°) [3941]

S = unitless scale variable defined in description.

NA = not applicable, TD = typically developing value, SE = standard error, p = p-value.

*Both Walk-DMC and GDI are scaled Z-scores that can exceed the mean typical value of 100, additionally Walk-DMC has a theoretical minimum value dependent upon the scaling values.

To obtain subject GMFM66 use equation: GMFM66 = Intercept + iβi Variablei.