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. 2022 Jul 4;13:906192. doi: 10.3389/fimmu.2022.906192

Table 2.

Potential evidence for the interactions between Imd pathway and other immune signaling pathways in T. molitor.

Genes Signaling pathway Pathogens Associated Organs Effects on the other immune pathway References
TmPGRP-LE Autophagy L. monocytogenes Whole body decreased larval survivability (50)
TmIKKγ Toll E. coli
S. aureus
C. albicans
Fat bodies
Hemocytes
Gut
Positive regulation of TmDorX2 (48)
TmIKKϵ Toll E. coli Fat bodies
Gut
Positive regulation of TmDorX2 (49)
TmRel Autophagy L. monocytogenes Fat bodies Positive regulation of TmAtg1 and TmVps34 (51)
Gut Positive regulation of TmVps34, TmAtg9, TmAtg5, and TmAtg8