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. Author manuscript; available in PMC: 2022 Jul 18.
Published in final edited form as: Clin Cancer Res. 2019 Jul 30;25(20):6107–6118. doi: 10.1158/1078-0432.CCR-18-3341

Figure 6:

Figure 6:

Correlation between molecular landscape and metabolic syndrome and/or history of hepatitis.

a) Correlation with metabolic syndrome: A significant number of patients with metabolic syndrome, 30% (3/10) had alterations detected in PDGFRA (p=0.0113), while patients without metabolic syndrome (n=30) had no alterations in this gene.

b) Correlation with hepatitis B status: A significant number of patients with hepatitis B 35.7% (5/9) had alterations in ERBB2 (p=0.0365), while HBV-negative patients had none.

c) Correlation with hepatitis C status: 16.7% (3/18) of patients with hepatitis C (HCV) had alterations in BRCA1 (p=0.0472), while HCV-negative patients had none.

d) Correlation with Child-Pugh score: 23.1% (3/13) of patients with Child-Pugh score B had alterations in PIK3CA (p=0.0341), versus 0% (0/27) Score A or C (0/1) (p=0.03).