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. 2021 Aug 26;29(1):225–236. doi: 10.1111/ene.15066

TABLE 4.

Cross‐sectional relationships of Diet Habits Questionnaire scores and meat and dairy consumption with clinically significant fatigue at 2.5‐year review.

n/N (%) aPR1 aPR2
DHQ score a
32–70 237/329 (72.0) 1.00 [Reference] 1.00 [Reference]
>70–80 214/310 (69.0) 0.96 (0.80, 1.15) 0.99 (0.82, 1.20)
>80–89 199/340 (58.5) 0.83 (0.69, 1.00) 0.89 (0.73, 1.08)
>89–100 141/287 (49.1) 0.70 (0.57, 0.86) 0.75 (0.61, 0.94)
Trend p < 0.001 p = 0.007
Consume meat? b
No 267/481 (55.5) 1.00 [Reference] 1.00 [Reference]
Yes 52/786 (66.8) 1.18 (1.02, 1.37) 1.09 (0.94, 1.27)
p = 0.027 p = 0.25
Consume dairy? c
No 290/526 (55.1) 1.00 [Reference] 1.00 [Reference]
Yes 498/737 (67.6) 1.21 (1.05, 1.40) 1.15 (0.99, 1.34)
p = 0.010 p = 0.067

Analyses by log‐binomial regression.

Model 1 adjusted for ongoing symptoms due to recent relapse. Model 2 further adjusted for age, sex, multiple sclerosis (MS) phenotype, P‐MSSS, and anti‐fatigue medication.

Results in boldface denote statistical significance (p < 0.05).

Abbreviations: aPR, adjusted prevalence ratio; DHQ, Diet Habits Questionnaire; P‐MSSS, Patient‐determined MS Severity Score;.

a

Analyses for DHQ score vs. clinically significant fatigue in Model 1 includes 1,266 people, thus excluding 80 people with missing data. Model 2 includes 1,196 people, thus excluding 150 people with missing data.

b

Analyses for meat consumption vs. clinically significant fatigue in Model 1 includes 1,267 people, thus excluding 79 people with missing data. Model 2 includes 1,197 people, thus excluding 149 people with missing data.

c

Analyses for dairy consumption vs. clinically significant fatigue in model 1 includes 1,263 people, thus excluding 83 people with missing data. Model 2 includes 1,193 people, thus excluding 153 people with missing data.