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Photomicrograph of an intestinal biopsy from a dog with granulomatous colitis shows strong immunolabeling for Escherichia coli in the cytoplasm of macrophages in the lamina propria (arrows). Red diaminobenzidine chromogen and hematoxylin counterstain, ×20 objective. Courtesy of Dr Patricia Ishii, DVM, Texas A&M University and Dr Paula Giaretta, DACVP, Universidade Federal de Minas Gerais, Brazil
