Skip to main content
. 2021 Oct 13;14(22):4878–4902. doi: 10.1002/cssc.202101635

Table 5.

Electrophilic aromatic sulfonylation with sulfonic acids.

Entry

Catalyst or promoter

Sulfonylating agent

Solvent

Conditions

Scope and yield

Ref.

1

P2O5/SiO2 (w/w 75 %, 1.2 g)

TsOH, PhSO3H, MsOH (3.1 mmol)

ArH (5 mL)

reflux, 30–105 min

15 examples 50–90 %

[24a]

2

Nafion‐H (400 mg, 50 wt%)

TsOH, PhSO3H, MsOH (5.0 mmol)

ArH (40 mL)

reflux, 8–20 h, Dean–Stark trap

11 examples 30–82 %

[24b]

3

Fe3+‐montmorillonite (0.2 g)

ArSO3H, MsOH, Ms2O, Ts2O (3.0 mmol)

ArH (5 mL)

reflux, 6–24 h

18 examples 23–94 %

[24c]

4

SiO2−AlCl3 (10 mol%)

TsOH, PhSO3H ArH/ ArSO3H=4 : 3 (mol)

80 °C, 1.3–2.7 h

22 examples 85–94 %

[24d]