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. 2019 Mar 21;33(7):7995–8007. doi: 10.1096/fj.201900017R

Figure 1.

Figure 1

Loss of Gal1 enhances HCC development in Mdr2‐KO/B6 mice. Incidence of tumors with diameters ≥0.3 cm. A) Tumor incidence of the following experimental groups of B6 mice: 16‐mo‐old females (Mdr2‐KO, n = 21 and dKO, n = 20), 16‐mo‐old males (Mdr2‐KO, n = 32 and dKO, n = 24), and 18‐mo‐old males (Mdr2‐KO, n = 26 and dKO, n = 31). B) Tumor incidence of the following experimental groups of FVB mice: 12‐mo‐old females (Mdr2‐KO, n = 15 and dKO, n = 12), 12‐mo‐old males (Mdr2‐KO, n= 19 and dKO, n= 12), and 14‐mo‐old males (Mdr2‐KO, n= 21 and dKO, n= 19). Only nodules with diameters ≥0.3 cm were counted. F, females; M, males. Statistical significance was calculated using Fisher's exact test. *P = 0.05 for 1‐tailed test and for tumors ≥0.3 cm, **P = 0.043 for 2‐tailed test and for tumors ≥0.3 cm, ## P = 0.0076 for 2‐tailed test for large tumors ≥0.8 cm.