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. 2019 Mar 21;33(7):7995–8007. doi: 10.1096/fj.201900017R

Figure 6.

Figure 6

Increased Ntrk2 expression in the liver of young dKO/B6 vs. Mdr2‐KO/B6 mice. A) Ntrk2 expression in the livers of 2‐mo‐old B6 Mdr2‐KO and dKO mice assessed by quantitative RT‐qPCR; n = 3–5 mice/genotype. Three transcript variants of murine Ntrk2 were detected. Only transcript variant 2 (NM_008745.3) could be distinguished from the other 2 transcripts by quantitative RT‐PCR. Left panel shows expression of the transcript variant 2, whereas right panel shows expression of all 3 transcripts together (NM_001025074.2, NM_008745.3, NM_001282961.1); 4–5 mice/assay were used. Means ± sd. **P < 0.005, ***P < 0.0005 in dKO vs. Mdr2‐KO mice (Student's t test). B) IHC of the Ntrk2 protein in the livers of 2‐mo‐old B6 Mdr2‐KO and dKO mice. Original magnification, ×200; scale bars 20 μm.