Table II.
SNOT‐22 Inter‐Domain Correlations and Domain Reliability.
| SNOT‐22 Domain | Pearson Correlations at Baseline, Phase 3 | Cronbach's Alpha at Baseline, Phase 2/Phase 3 | Test–Retest ICC (95% CI), Phase 2/Phase 3 | |||||
|---|---|---|---|---|---|---|---|---|
| Nasal | Ear/Facial | Sleep | Function | Emotion | No Change on RS VAS * | No Change on NPS † | ||
| Nasal | 1.0 | – | – | – | – | 0.84/0.83 | 0.82 (0.69, 0.90)/0.86 (0.84, 0.88) | 0.83 (0.66, 0.92)/0.84 (0.80, 0.88) |
| Ear/facial | 0.699 | 1.0 | – | – | – | 0.81/0.81 | 0.84 (0.72, 0.91)/0.76 (0.72, 0.80) | 0.76 (0.54, 0.88)/0.76 (0.70, 0.81) |
| Sleep | 0.609 | 0.686 | 1.0 | – | – | 0.89/0.91 | 0.88 (0.78, 0.94)/0.77 (0.74, 0.81) | 0.86 (0.71, 0.93)/0.78 (0.72, 0.83) |
| Function | 0.554 | 0.731 | 0.877 | 1.0 | – | 0.90/0.92 | 0.90 (0.82, 0.95)/0.75 (0.71, 0.79) | 0.91 (0.81, 0.96)/0.78 (0.72, 0.83) |
| Emotion | 0.533 | 0.707 | 0.749 | 0.870 | 1.0 | 0.87/0.86 | 0.84 (0.71, 0.91)/0.80 (0.76, 0.83) | 0.85 (0.70, 0.93)/0.80 (0.75, 0.85) |
| Total | – | – | – | – | – | 0.94/0.94 | 0.92 (0.85, 0.96)/0.86 (0.84, 0.88) | 0.89 (0.77, 0.95)/0.85 (0.81, 0.88) |
*
No change in rhinosinusitis VAS categories between Week 8 and Week 12.
†
No change in NPS between Week 8 and Week 12.
CI = confidence interval; ICC = intraclass correlation coefficient; NPS = Nasal Polyps Score; RS VAS = rhinosinusitis Visual Analog Scale; SNOT‐22 = 22‐item Sinonasal Outcome Test.