FIGURE 4.

Changes in collagen formation and degradation according to both fibrosis and hepatic inflammation for collagens type III (A), type IV (B), type V (C) and type VI (D). Boxplots of collagen formation markers (PRO‐C3 to PRO‐C6) and collagen degradation markers (C3M to C6M), divided into fibrosis stages F0‐2 vs F3‐4, and subdivided according to hepatic inflammatory activity scores. Low denotes none or mild inflammation (score 0‐2). High denotes moderate or severe inflammation (score 3‐5). To compare formation and degradation markers, we log‐transformed their concentrations