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. 2021 Apr 7;47(7):931–941. doi: 10.1111/nan.12710

TABLE 2.

Demographic and clinicopathologic features of cases in Cluster 2

Cluster 2–1 Cluster 2–2 Cluster 2–3 Cluster 2–4 p value
Number of cases 568 105 204 149
Male, No. (%) 306 (54%) 49 (47%) 102 (50%) 76 (51%) 0.666
Age at death, years* 73 ± 7 81 ± 7 76 ± 7 77 ± 8 <0.001
Pathologic diagnosis of PSP 566 (99%) 103 (98%) 204 (100%) 147 (99%)
Concurrent AD** 21 (4%) 56 (53%) 9 (4%) 11 (7%) <0.001
Clinical diagnosis*** <0.001
RS 483 (85%) 71 (68%) 179 (88%) 105 (70%)
CBS 40 (7%) 15 (14%) 8 (4%) 17 (11%)
Other 45 (8%) 19 (18%) 17 (8%) 27 (18%)

Data are displayed as n (%), mean ± SD and median (25th, 75th range).

*Age is significantly different between all clusters except Clusters 2–3 and 2–4.

**The frequency of concurrent AD is significantly different between Cluster 2–2 and all other clusters.

***The frequency of clinical diagnosis is significantly different between Clusters 2–1 and 2–2; and Clusters 2–2 and 2–3. Pairwise comparison is done using Bonferroni correction.