TABLE 2.

General Characteristics and Blood Chemistry of Subjects

Characteristics and blood chemistry	Treatment			Placebo			P1	P2	P3
	Baseline	Week 6	Week 12	Baseline	Week 6	Week 12
Age (year)	53.3 (47–57)	‐	‐	52.6 (45–58)	‐	‐	.055	‐	‐
Weight (kg)	59.79 ± 10.18	59.41 ± 10.16	59.20 ± 10.17	62.13 ± 11.19	61.79 ± 11.17	60.45 ± 13.67	>.999	>.999	>.999
BMI (kg/m2)	23.94 ± 4.03	23.82 ± 4.01	23.08 ± 5.14	24.72 ± 4.28	24.58 ± 4.21	24.47 ± 4.33	>.999	>.999	>.999
Body fat (%)	34.42 ± 6.27	34.18 ± 6.41	33.86 ± 6.52	36.21 ± 6.49	36.08 ± 6.54	36.00 ± 6.71	>.999	>.999	>.999
Blood pressure (mmHg)
Systolic	123.1 ± 19.32	122.0 ± 18.45	120.8 ± 16.30	126.5 ± 13.82	124.1 ± 11.63	124.7 ± 15.54	>.999	>.999	>.999
Diastolic	78.92 ± 11.27	78.78 ± 9.360	77.08 ± 12.15	82.36 ± 9.209	80.36 ± 10.07	78.62 ± 10.55	.662	>.999	>.999
Pulse rate (bpm)	72.60 ± 9.52	72.92 ± 10.57	72.58 ± 9.47	73.96 ± 11.00	72.73 ± 10.18	75.94 ± 10.75	>.999	>.999	>.999
BUN (mg/dl)	12.58 ± 2.41	12.54 ± 2.44	12.94 ± 2.46	12.58 ± 1.73	13.79 ± 2.56	13.73 ± 2.59	>.999	.358	>.999
Cr (mg/dL)	0.71 ± 0.16	0.87 ± 0.17	0.66 ± 0.17	0.72 ± 0.22	0.82 ± 0.22	0.67 ± 0.17	>.999	.980	0.999
AST (U/L)	21.89 ± 4.80	23.17 ± 4.71	21.76 ± 4.55	23.29 ± 5.44	23.84 ± 8.11	23.55 ± 6.37	>.999	>.999	>.999
ALT (U/L)	20.59 ± 8.61	20.14 ± 6.98	21.80 ± 7.64	18.33 ± 5.37	18.96 ± 7.04	21.92 ± 9.59	>.999	>.999	>.999

Values are means ± SD. Means in a row with superscript letters without a common letter differ within group; Significant differences at p < .05. P1 = Comparison of mean between the two groups at baseline; P2 = Comparison of mean between the two groups at week 6; P3 = Comparison of mean between the two groups at week 12; Significant differences at p < .05.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; Cr, creatinine.