Table 5.
Synonymous SNPs identified between vaccine strains and vaccine‐associated viruses. The position of each SNP is provided for KX764645_Neethling‐LSD‐Vaccine‐OBP and AF409137_ Neethling‐LSD‐Warmbaths‐RSA‐2000
| # | Nucleotide in vaccine strains (KX764645_Neethling‐LSD‐Vaccine‐OBP) | Nucleotide in vaccine‐associated viruses | Nucleotide in wild type (AF409137_Neethling‐LSD‐Warmbaths‐RSA‐2000) | ORF affected | Amino acid position in protein | Resulting amino acid change |
|---|---|---|---|---|---|---|
| 1 | 11,507 (C) | T | 11,512 (C) | LW017 | 12 | L = L |
| 2 | 39,546 (T) | C | 39,567 (T) | LW045 | 212 | T = T |
| 3 | 43,846 (T) | C | 43,866 (C) | LW049 | 249 | G = G |
| 4 | 56,951 (C) | G | 56,977 (C) | LW066 | 60 | A = A |
| 5 | 61,240 (T) | C | 61,269 (T) | LW071 | 416 | G = G |
| 6 | 64,167 (C) | T | 64,196 (T) | LW072 | 68 | S = S |
| 7 | 71,998 (G) | A | 72,022 (G) | LW083 | 572 | A = A |
| 8 | 81,723 (A) | G | 81,747 (A) | LW088 | 488 | P = P |
| 9 | 85,571 (C) | T | 85,595 (T) | LW090 | 65 | A = A |
| 10 | 85,990 (A) | T | 86,014 (A) | LW091 | 85 | S = S |
| 11 | 87,868 (G) | A | 87,892 (A) | LW094 | 441 | G = G |
| 12 | 103,332 (A) | G | 103,405 (A) | LW111 | 60 | S = S |
| 13 | 104,442 (C) | T | 104,509 (T) | LW112 | 193 | P = P |
| 14 | 109,433 (G) | A | 109,499 (G) | LW116 | 863 | L = L |
| 15 | 109,664 (T) | C | 109,730 (T) | LW116 | 940 | G = G |
| 16 | 118,583 (T) | C | 118,713 (T) | LW129 | 61 | D = D |
| 17 | 125,940 (C) | T | 126,035 (T) | LW135 | 231 | S = S |
| 18 | 131,803 (C) | T | 131,901 (T) | LW144a | 25 | G = G |
| 19 | 133,229 (T) | C | 13,332 (T) | LW145 | 574 | C = C |
| 20 | 136,014 (A) | G | 136,132 (G) | LW151 | 540 | E = E |
| 21 | 147,891 (A) | T | 147,946 (A) | LW152 | 389 | I = I |