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Linear mixed‐effects model parameters
| Parameter | Description | Estimate | RSE (%) | P‐value |
|---|---|---|---|---|
| θ0 | Intercept (ms) | −0.269 | 237.15 | 0.674 |
| η0 | Random effect for intercept (ms) | 5.350 | ||
| θ1 | Slope (ms/ (ng/mL)) | 0.00337 | 17.003 | <.001 |
| η1 | Random effect for slope (ms/(ng/mL)) | 2.271 | ||
| θ2 | Impact of baseline QTcF on ΔQTcF | −0.119 | 25.90 | <.001 |
| ɛ | Residual variability (ms) | 6.452 |
QTcF, Fridericia‐corrected QT interval; RSE, relative standard error.
