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. 2021 Oct 12;32(Suppl 21):5–27. doi: 10.1111/clr.13860

TABLE 6.

Biological outcomes according to the implant placement and loading protocols (NA = not applicable; NR = not reported)

Study Placement and loading protocol Type of loading Mean ± SD follow‐up (months) No. implants placed No. implants available at follow‐up Implant survival rate Mean ± SD MBL changes at follow‐up (mm) Mean ± SD on peri‐implant inflammation (different indexes) Mean ± SD soft‐tissue recession at follow‐up (mm) Mean ± SD width KT at follow‐up (mm) Mean ± SD PI at follow‐up Mean (SD) PD at follow‐up (mm) No. of reported biological complications Rate of biological complications (%) (except implant failure)
An et al. (2019) DPIL Non‐functional 36 68 68 100% 0.42 ± 0.39 0.65 ± 0.81 (Gingival Index) NR NR 0.35 ± 0.64 2.68 (1.00) 0 0%
Daher et al. (2019) DPIL Functional 36 80 69 95.5% 0.78 ± 0.72 NR NR NR NR NR 0 0%
DPDL NA 36 80 71 96.3% 0.91 ± 1.05 NR NR NR NR NR 2 implants with peri‐implantitis 2.8%
Degidi et al. (2011) DPIL Non‐functional 36 48 48 100% 0.57 ± 0.52 NR NR NR NR NR 0 0%
Fung et al. (2011) DPIL Functional 36 42 40 95.2% 0.26 ± 0.44 0.25 ± 0.30 (Sulcus Bleeding Index) NR NR NR 2.82 (0.75) 0 0%
Göthberg et al. (2018) DPIL Functional 60 78 62 94.9% NR NR NR NR NR 3.15 (0.87) 3 implants with peri‐implantitis 4.8%
DPDL NA 60 72 64 97.2% NR NR NR NR NR 3.18 (0.94)

2 implants with peri‐implantitis

2 implants with fistula

6.3%
Oxby et al. (2015) DPEL NA 55 107 107 100% 0.28 ± 0.88 NR NR NR NR NR 1 implant with soft‐tissue recession 0.9%
IPEL NA 55 67 67 100% 0.34 ± 1.48 NR NR NR NR NR 1 implant with soft‐tissue recession 1.5%
Payer et al. (2010) DPIL Non‐functional 96 40 18 95% 0.88 ± 1.15 NR NR NR NR NR 1 implant with peri‐implantitis 5.6%
Romanos et al. (2016) DPIL Functional 145.7 ± 10.7 36 30 100% 0.57 ± 1.06 0.07 ± 0.25 (Sulcus Bleeding Index) 0.30 ± 0.84 1.73 ± 1.36 mm 0.56 ± 0.94 2.53 (0.63) 0 0%
DPDL NA 145.7 ± 10.7 36 30 100% 1.12 ± 1.30 0.00 ± 0.00 (Sulcus Bleeding Index) 0.20 ±0.48 2.00 ± 1.23 mm 0.43 ± 0.63 2.6 (0.50) 0 0%
Si et al. (2016) DPDL NA 66 21 19 90.5% NR NR NR NR NR NR 2 implants with peri‐implantitis 10.5%
Siebers et al. (2010) DPIL Both 45.1 ± 7.2 33 32 97% 2.15 ± 0.81 1.59 ± 1.39 (from 0 to 6) NR NR NR NR NR
DPDL NA 55.7 ± 16.2 46 46 100% 2.46 ± 0.96 2.91 ± 2.11 (from 0 to 6) NR NR NR NR NR
IPIL Both 47.64 ± 6.48 20 17 90% 1.57 ± 0.91 1.76 ± 1.79 (from 0 to 6) NR NR NR NR NR
Simons et al. (2015) DPDL NA 48 151 151 98.3% 0.5 ± 0.68 NR NR NR NR NR NR
Spies et al. (2015) DPIL Non‐functional 60 26 26 100% 1.14 ± NR 1.1 ± NA (modified Bleeding Index) NR NR 0.72 ± NR NR 0 0
Van Nimwegen et al. (2015) DPDL NA 60 70 58 97.1% NR 40 ± NR (Bleeding Index) NR NR NR 3.33 (1.73) 2 implants with peri‐implantitis 3.4%
Vogl et al. (2019) DPIL Functional 36 19 17 100% 0.37 ± 0.46 NR NR NR 1.6 ± 0.7 NR 0 0%
DPIL Non‐functional 36 32 30 97% 0.39 ± 0.47 NR NR NR 1.6 ± 0.7 NR 0 0%