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. 2021 Sep 4;27(6):984–992. doi: 10.1111/hae.14398

TABLE 3.

Summary of time to first ADA detection during treatment with emicizumab

Time to first treatment‐induced or treatment‐boosted ADA
PwHA (N = 668) n ≤1 month >1 to ≤2 months >2 to ≤3 months >3 to ≤6 months >6 months
ADA‐positive PwHA 34 3 (8.8%) 4 (11.8%) 9 (26.5%) 14 (41.2%) 4 (11.8%)
nADA‐positive PwHA a 18 2 (11.1%) 2 (11.1%) 7 (38.9%) 6 (33.3%) 1 (5.6%)

Abbreviations: ADA, anti‐drug antibody; nADA, neutralising anti‐drug antibody; PwHA, persons with haemophilia A.

a

Including ADA‐positive PwHA with decreased exposure.