Figure 1.

Diversity analysis of bacterial and fungal communities in patients with early‐stage melanoma. (a, b) Alpha diversity analysis using synthetic indexes of richness and evenness for (a) bacterial and (b) fungal communities. (c–e) Principal coordinates analysis (PCoA) ordination based on Bray–Curtis distance of samples from patients with melanoma and healthy controls considering bacterial community alone (c), fungal community alone (d) and combined bacterial and fungal community (e) datasets. (f) Putative differential bacterial (at the genus level) and fungal (at the species level) markers between patients with early‐stage melanoma and controls assessed by linear discriminant analysis (LDA) effect size analysis (alpha = 0.05; LDA cutoff = 2). OTU, operational taxonomic unit.