Figure 2.

Differences in microbial communities of patients with early‐stage melanoma with respect to invasion and regression. (a, b) Principal coordinates analysis (PCoA) ordination based on Bray–Curtis distance of the combined bacterial and fungal communities in patients with melanoma. Points are coloured based on melanoma invasion features. (c) Graphical representation of the results of the ANOSIM statistical test. (d) Distribution of patients with melanoma in the different classes of melanoma invasion and regression. (e, f) PCoA ordination based on Bray–Curtis distance of the fungal community in patients with melanoma. Points are coloured based on regression features. (g) Venn diagram showing intersections between differentially abundant zero‐radius operational taxonomic units found in the comparison between (i) invasive vs. in situ melanoma (‘invasivity’), (ii) regressed vs. not regressed melanoma (‘regression’) and (iii) control vs. melanoma (C vs. M).