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. 2021 Sep 3;185(11):3466–3475. doi: 10.1002/ajmg.a.62470

TABLE 6.

Revised IOR Classification: disease severity

Criteria Class Subclass
No deformities—no functional limitations I IA ≤5 sites with OC
IB >5 sites with OC
Deformities—no functional limitations II IIA ≤2 sites with deformities
IIB >2 sites with deformities
Deformities—functional limitations III IIIA 1 site with functional limitation
IIIB >1 site with functional limitation

Abbreviations: IOR, Istituto Ortopedico Rizzoli; OC, osteochondroma(s).