FIGURE 2.

Subcellular location of the differentially expressed genes (DEGs) and genes in the incisional secretome. A, The number (left) and proportion (right) of genes in six categories: secreted, extracellular, plasma membrane, cytoplasm, nucleus, and uncharacterized/other. B, Heatmap of the incisional secretome. C, The DEGs in the secretome at each timepoint with several representative genes labeled. For the scatter plot, the expression ratio between each timepoint and untreated control is plotted versus average sFPKM using logarithmic scales. D, The top 50 DEGs in the incisional secretome. Genes are arranged according to time after incision. Note the stepwise temporal patterns of transcript increases in B and D. d, day(s); hr or h, hour(s); Unt, untreated control