TABLE 5.
Top 30 differentially induced transcripts related to wound healing
| Gene symbol | Gene name | sFPKM | Expression ratio compared to Unt | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Unt | 1 hr | 6 hr | 1d | 3 d | 6 d | 12 d | |||
| Il6 | Interleukin 6 | 0.1 | 55.0 | 93.8 | 13.3 | 7.4 | 3.0 | 1.7 | 781.8 |
| Cxcl2 | C‐X‐C motif chemokine ligand 2 | 0.2 | 105.3 | 63.9 | 60.4 | 11.6 | 2.9 | 9.7 | 657.9 |
| S100a9 | S100 calcium‐binding protein A9 | 20.9 | 470.6 | 2417.2 | 5075.9 | 1354.9 | 133.6 | 591.2 | 242.4 |
| Reg3g | Regenerating family member 3 gamma | 0.1 | 0.1 | 22.8 | 3.5 | 0.9 | 0.2 | 0.2 | 163.0 |
| S100a8 | S100 calcium‐binding protein A8 | 23.9 | 129.9 | 1126.9 | 3585.5 | 996.8 | 117.8 | 576.5 | 150.2 |
| Il24 | Interleukin 24 | 1.8 | 3.0 | 55.7 | 167.8 | 10.2 | 2.6 | 7.7 | 91.7 |
| Mmp12 | Matrix metallopeptidase 12 | 0.3 | 0.2 | 7.8 | 24.2 | 22.7 | 16.4 | 23.4 | 75.5 |
| Il1b | Interleukin 1 beta | 2.0 | 68.1 | 141.7 | 62.3 | 25.5 | 10.6 | 24.3 | 69.8 |
| Hmox1 | Heme oxygenase 1 | 17.9 | 20.1 | 1125.7 | 346.3 | 354.4 | 93.4 | 110.5 | 62.7 |
| Nos2 | Nitric oxide synthase 2 | 0.1 | 0.1 | 4.1 | 2.6 | 0.3 | 0.2 | 0.3 | 37.0 |
| Bnc1 | Basonuclin 1 | 1.0 | 0.6 | 9.9 | 34.5 | 8.5 | 2.4 | 4.6 | 35.9 |
| Serpine1 | Serpin family E member 1 | 8.4 | 151.2 | 282.7 | 151.0 | 172.7 | 47.4 | 110.4 | 33.7 |
| Tnc | Tenascin C | 11.8 | 14.7 | 48.3 | 121.8 | 355.9 | 95.3 | 122.6 | 30.3 |
| Ccl20 | C‐C motif chemokine ligand 20 | 0.5 | 1.9 | 14.9 | 11.4 | 1.9 | 0.3 | 1.0 | 28.1 |
| Ccl2 | C‐C motif chemokine ligand 2 | 103.2 | 1083.2 | 2878.0 | 724.1 | 287.0 | 105.7 | 164.6 | 27.9 |
| Slc7a11 | Solute carrier family 7 member 11 | 1.0 | 1.0 | 20.6 | 16.5 | 4.9 | 1.4 | 2.4 | 21.6 |
| Clec7a | C‐type lectin domain family 7, member A | 1.9 | 7.8 | 36.6 | 19.4 | 21.9 | 6.0 | 8.2 | 19.3 |
| Tgfa | Transforming growth factor alpha | 2.9 | 1.6 | 23.3 | 51.9 | 8.2 | 4.8 | 7.2 | 17.8 |
| F2rl2 | Coagulation factor II (thrombin) receptor‐like 2 | 1.7 | 3.0 | 30.1 | 4.2 | 5.4 | 1.6 | 3.3 | 17.7 |
| Jaml | Junction adhesion molecule like | 0.3 | 1.4 | 4.5 | 2.3 | 1.9 | 1.3 | 1.5 | 16.2 |
| Plaur | Plasminogen activator, urokinase receptor | 7.9 | 22.5 | 124.2 | 43.6 | 30.3 | 18.4 | 40.9 | 15.7 |
| Timp1 | TIMP metallopeptidase inhibitor 1 | 161.8 | 227.3 | 2421.1 | 1805.8 | 2035.9 | 725.2 | 560.2 | 15.0 |
| Nrg1 | Neuregulin 1 | 1.7 | 1.2 | 12.2 | 24.8 | 5.1 | 1.7 | 4.2 | 14.7 |
| Cdh3 | Cadherin 3 | 1.9 | 1.5 | 9.6 | 28.1 | 10.6 | 5.1 | 5.5 | 14.7 |
| Selp | Selectin P | 1.1 | 4.2 | 13.7 | 4.4 | 4.5 | 2.6 | 6.1 | 12.8 |
| Fcgr3a | Fc fragment of igg, low affinity iiia, receptor | 0.6 | 0.7 | 0.9 | 3.7 | 7.6 | 3.8 | 1.7 | 12.7 |
| Postn | Periostin | 96.2 | 116.5 | 118.9 | 140.9 | 740.0 | 1170.0 | 1164.2 | 12.2 |
| Mdk | Midkine | 3.4 | 2.9 | 2.6 | 3.6 | 10.1 | 40.1 | 35.8 | 11.8 |
| Slc11a1 | Solute carrier family 11 member 1 | 2.7 | 4.3 | 29.0 | 17.6 | 16.3 | 5.6 | 5.4 | 10.9 |
| C3 | Complement component 3 | 1.3 | 2.1 | 11.7 | 4.4 | 9.9 | 13.2 | 11.2 | 10.5 |
Although the actual sFPKM values of measurement had two decimal places, the values were rounded off and expressed using one decimal place in this table. The expression ratio was calculated using the actual values. The actual values are found in Table S1.
Abbreviations: d, days; hr, hours; Max, maximum expression level; Unt, untreated control.