TABLE 6.
Top 30 differentially induced transcripts related to sensory perception of pain
| Gene symbol | Gene name | sFPKM | Expression ratio compared to Unt | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Unt | 1 hr | 6 hr | 1d | 3 d | 6 d | 12 d | |||
| Gip | Gastric inhibitory polypeptide | 0.1 | 0.1 | 0.9 | 17.5 | 9.0 | 0.8 | 1.2 | 145.4 |
| Ccl3 | C‐C motif chemokine ligand 3 | 2.1 | 41.0 | 99.8 | 56.1 | 30.4 | 8.0 | 11.8 | 46.6 |
| Il10 | Interleukin 10 | 0.2 | 6.0 | 0.7 | 0.8 | 0.6 | 0.3 | 0.5 | 37.6 |
| Ccl2 | C‐C motif chemokine ligand 2 | 103.2 | 1083.2 | 2878.0 | 724.1 | 287.0 | 105.7 | 164.6 | 27.9 |
| Ptgs2 | Prostaglandin‐endoperoxide synthase 2 | 1.9 | 36.1 | 26.6 | 36.5 | 8.8 | 6.4 | 7.0 | 19.6 |
| Fcgr3a | Fc fragment of igg, low affinity iiia, receptor | 0.6 | 0.7 | 0.9 | 3.7 | 7.6 | 3.8 | 1.7 | 12.7 |
| Cxcr4 | C‐X‐C motif chemokine receptor 4 | 3.5 | 14.0 | 34.6 | 17.5 | 25.4 | 14.6 | 13.5 | 9.8 |
| Fabp5 | Fatty acid‐binding protein 5, epidermal | 1986.4 | 1564.8 | 4252.1 | 13 570.6 | 6060.4 | 3686.4 | 3512.8 | 6.8 |
| Penk | Proenkephalin | 1.5 | 2.9 | 2.4 | 1.5 | 10.1 | 5.4 | 8.0 | 6.7 |
| Il1rn | Interleukin 1 receptor antagonist | 14.1 | 10.0 | 90.5 | 42.5 | 28.1 | 21.8 | 20.9 | 6.4 |
| Cnr2 | Cannabinoid receptor 2 | 0.8 | 1.4 | 4.9 | 2.2 | 3.0 | 1.7 | 1.9 | 6.1 |
| Ednrb | Endothelin receptor type B | 3.2 | 3.6 | 16.1 | 6.5 | 6.5 | 4.8 | 6.8 | 5.0 |
| Tmem120a | Transmembrane protein 120A | 15.7 | 16.3 | 60.4 | 73.0 | 60.7 | 32.8 | 31.2 | 4.7 |
| Ngf | Nerve growth factor | 4.9 | 5.8 | 22.8 | 17.8 | 9.0 | 6.0 | 7.5 | 4.6 |
| Cacnb3 | Calcium voltage‐gated channel auxiliary subunit beta 3 | 2.9 | 2.5 | 3.0 | 4.0 | 10.0 | 13.4 | 11.1 | 4.6 |
| Tac4 | Tachykinin 4 (hemokinin) | 0.8 | 0.9 | 1.5 | 2.7 | 3.2 | 2.3 | 3.4 | 4.5 |
| Ptafr | Platelet‐activating factor receptor | 5.7 | 9.2 | 21.0 | 19.7 | 18.7 | 12.2 | 15.6 | 3.7 |
| Cxcl12 | C‐X‐C motif chemokine ligand 12 | 24.6 | 22.0 | 23.0 | 23.9 | 42.3 | 91.2 | 76.7 | 3.7 |
| P2rx4 | Purinergic receptor P2X 4 | 13.0 | 12.8 | 20.3 | 28.7 | 47.7 | 32.1 | 24.1 | 3.7 |
| Pawr | Pro‐apoptotic WT1 regulator | 3.8 | 2.9 | 5.6 | 12.9 | 6.8 | 7.1 | 6.5 | 3.4 |
| Ngfr | Nerve growth factor receptor | 0.8 | 0.9 | 2.0 | 1.2 | 1.5 | 2.6 | 1.7 | 3.3 |
| Ednra | Endothelin receptor type A | 1.8 | 1.5 | 2.1 | 6.0 | 5.3 | 5.8 | 5.0 | 3.2 |
| Il1a | Interleukin 1 alpha | 2.3 | 1.8 | 7.5 | 7.3 | 2.2 | 2.6 | 3.1 | 3.2 |
| Lxn | Latexin | 24.6 | 18.7 | 34.5 | 77.7 | 74.9 | 37.4 | 29.2 | 3.2 |
| F2r | Coagulation factor II (thrombin) receptor | 6.8 | 7.3 | 7.4 | 5.5 | 13.2 | 12.7 | 20.5 | 3.0 |
| Fyn | FYN proto‐oncogene, Src family tyrosine kinase | 21.5 | 21.7 | 53.2 | 19.6 | 31.6 | 35.3 | 38.4 | 2.5 |
| Nipsnap1 | Nipsnap homolog 1 (C elegans) | 3.0 | 3.2 | 2.3 | 5.4 | 7.4 | 7.2 | 4.9 | 2.4 |
| Ctss | Cathepsin S | 74.8 | 71.5 | 81.8 | 92.4 | 180.3 | 102.7 | 99.1 | 2.4 |
| Arrb2 | Arrestin, beta 2 | 19.7 | 22.6 | 27.4 | 41.4 | 46.9 | 28.8 | 22.2 | 2.4 |
| Cdk5 | Cyclin‐dependent kinase 5 | 16.2 | 17.7 | 15.7 | 26.6 | 37.8 | 36.5 | 29.6 | 2.3 |
Although the actual sFPKM values of measurement had two decimal places, the values were rounded off and expressed using one decimal place in this table. The expression ratio was calculated using the actual values. The actual values are found in Table S1.
Abbreviations: d, days; hr, hours; Max, maximum expression level; Unt, untreated control.