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ALT and virology dynamics in patients with grade 3 or 4 ALT elevation. Treatment allocations per patient: S21–017, 100 mg Vonafexor once daily; S21–018, 200 mg Vonafexor once daily; S21–022, 150 mg Vonafexor twice daily +Peg‐IFNα2a; S42–011, 150 mg Vonafexor twice daily +Peg‐IFNα2a. ALT, alanine transaminase; Peg‐IFNα2a, pegylated‐interferon α2a. Dotted lines are HBV DNA changes and filled lines are ALT changes
