Fig. 1.

Quantitative relationship between culturable virus and sample viral load. Day 3 viral culture supernatant from each cultured sample and its corresponding respiratory sample were each analysed by RT-qPCR to determine respective viral loads (n = 181). The viral load in genome copies/mL (logarithmic scale) of culture supernatant is plotted against the genome copies/mL (logarithmic scale) of the original patient sample. Linear regression (solid line) with 95% CIs (dashed lines) is shown. R² = 0.55. Samples with negative viral cultures (see Materials and Methods) for representation are assigned a y-axis, value of 10⁰, and are demarcated as coloured brown dots.