. 2021 Sep 30;106(11):2198–2209. doi: 10.1113/EP089975

TABLE 2.

Cardiopulmonary exercise test

Parameter	Baseline	4 weeks	8 weeks
Rest
${\dot{V}}_{O_{2}}$ (ml/kg/min)	4.55 ± 0.6	5.05 ± 0.9	4.69 ± 1.0
${\dot{V}}_{C O_{2}}$ (ml/kg/min)	4.62 ± 0.7	5.21 ± 1.1	4.58 ± 1.2
${\dot{V}}_{E}$ (l/kg/min)	0.17 ± 0.03	0.19 ± 0.1	0.17 ± 0.03
$P_{ETC O_{2}}$ (mmHg)	31.2 ± 2.3	31.5 ± 1.8	29.5 ± 2.2
$P_{ET O_{2}}$ (mmHg)	53.6 ± 3.3	53.2 ± 2.3	54.2 ± 1.1
R _f (bpm)	17.6 ± 2.1	17.5 ± 2.4	17.1 ± 2.7
HR (bpm)	81.9 ± 11.3	77.7 ± 8.5	72.1 ± 2.8
$S_{p O_{2}}$ (%)	84.3 ± 2.8	85.2 ± 3.3	85.4 ± 2.1
SBP (mmHg)	115.8 ± 10.8	110.1 ± 11.1	109.8 ± 14.6
DBP (mmHg)	70.6 ± 8.1	67.5 ± 7.1	66.1 ± 9.6
Peak exercise
${\dot{V}}_{O_{2}}$ (ml/kg/min)	33.8 ± 6.7	36.4 ± 5.4	37.2 ± 5.6^*
${\dot{V}}_{C O_{2}}$ (ml/kg/min)	40.7 ± 7.4	42.2 ± 5.7	42.6 ± 5.8
${\dot{V}}_{E}$ (l/kg/min)	1.8 ± 0.5	1.9 ± 0.5	2.0 ± 0.4
$P_{ETC O_{2}}$ (mmHg)	24.8 ± 4.1	24.4 ± 2.8	23.6 ± 2.5
$P_{ET O_{2}}$ (mmHg)	63.3 ± 3.0	63.0 ± 2.0	63.1 ± 1.5
R _f (bpm)	52.3 ± 8.8	57.4 ± 9.6	56.6 ± 6.8
HR (bpm)	153.4 ± 22.4	164.9 ±19.1	169.5 ± 16.5^*
$S_{p O_{2}}$ (%)	80.1 ± 3.5	81.8 ± 3.9	79.6 ± 2.4
SBP (mmHg)	156.3 ± 17.5	140.0 ± 10.4^**	148.3 ± 15.8
DBP (mmHg)	89.3 ± 2.9	81.4 ± 5.9^*	86.0 ± 4.8
Workload (W)	172.5 ± 26.6	198.8 ± 27.5^***	210.0 ± 27.8^**

All values are presented as means ± SD. Differences were assessed using repeated measures one‐way ANOVA or Friedman tests followed by Tukey's or Dunn's multiple comparisons, respectively.

^* P < 0.05, ^** P < 0.01 vs. baseline. Abbreviations : ${\dot{V}}_{C O_{2}}$ , CO₂ production; ${\dot{V}}_{O_{2}}$ , O₂ consumption; ${\dot{V}}_{E}$ , pulmonary ventilation; $P_{ETC O_{2}}$ , end‐tidal CO₂ partial pressure; $P_{ET O_{2}}$ , end‐tidal O₂ partial pressure; R _f, respiratory rate; HR, heart rate; $S_{p O_{2}}$ , peripheral oxygen saturation; SBP, systolic blood pressure; DBP, diastolic blood pressure.