TABLE 1.
Description of included studies
| Author/Year | Study design | Subjects n | Mean age | Implant system | Design prosthesis | Number of prosthesis | Digital fabrication | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Data acquisition | Laboratory scanner | CAD system | CAM system | Type of CAM | Location of CAM | Finalization of prosthesis | |||||||
| Di Fiore et al. (2018) | prospective cohort study with a crossover design | 10 | na | na | fixed | 10 | Cerec Omnicam | CEREC Biogeneric | CEREC MC XL, Sirona |
Subtractive (monolithic crown) |
point‐of‐care | point‐of‐care | |
| Joda and Bragger (2014) | prospective cohort study | 6 | na | Straumann Tissue Level | fixed | 3 | iTero, Align Technology | Straumann CARES | Straumann CARES |
subtractive (monolithic crown) |
implant manufacturer | dental laboratory | |
| 3 | subtractive (customized abutment, monolithic crown) | ||||||||||||
| Joda and Bragger (2014) | prospective cohort study with a crossover design | 20 | 55.4y | Straumann Tissue Level | fixed | 20 | iTero, Align Technology | Straumann CARES | Straumann CARES | subtractive (customized abutment, crown coping) | implant manufacturer | dental laboratory | |
| Joda and Bragger (2016) | Randomized controlled trial | 20 | 55.4y | Straumann Tissue Level | fixed | 10 | iTero, Align Technology | Straumann CARES | Straumann CARES | subtractive (monolithic crown) | implant manufacturer | dental laboratory | |
| 10 | subtractive (customized abutment, model) | ||||||||||||
| Mangano, Margiani, et al. (2019) | retrospective cohort study | 25 | 51.1 | Exacone, Leone Implants | fixed | 40 | CS 3,600, Carestream Dental | Exocad DentalCAD, Exocad | Roland DWX−50, Roland Easy Shape | subtractive (abutment and monolithic crown | dental laboratory | dental technician | |
| Mangano and Veronesi (2018) | randomized controlled clinical trial | 50 | 52.6 | Exacone, Leone Implants | fixed | 25 | CS 3,600, Carestream Dental | Exocad DentalCAD, Exocad | Roland DWX−50, Roland Easy Shape | subtractive | dental laboratory | dental technician | |
| Mangano, Mangano, et al. (2019) | prospective cohort study | 15 | 68.8 | BTSafe, BTK | removable | 15 | CS 3,600, Carestream Dental | Exocad DentalCAD, Exocad | 3500PD | additive (prototype bar) | dental laboratory | ||
| Roland DWX−51, Roland Easy Shape | subtractive (PEEK bar) | dental laboratory | |||||||||||
| Pan et al. (2019) | prospective cohort study with a crossover design | 40 | 45.1y | Straumann Tissue Level and Bone Level | fixed | 40 | Trios, 3Shape | 3Shape Designer | Zentotec Select Hybrid | subtractive (monolithic crown) | dental laboratory | dental laboratory | |
| 40 | conventional | D2000, 3Shape | |||||||||||
| Zhang, Qiu, et al. (2019) | Randomized controlled trial | 33 | 46.8y | CAMLOG SCREW‐LINE, Camlog Biotechnologies AG | fixed | 17 | Cerec Omnicam | CEREC | CEREC MC XL Premium |
subtractive (monolithic crown) |
point‐of‐care | point‐of‐care (dentist, dental technician) | |
| 16 | conventional | Trios lab, 3Shape | Trios lab, 3Shape | centralized manufacture | subtractive (crown coping) | unknown | |||||||