Table 2.
Annotated functions of PIK3CA with its interacting proteins/genes based on the protein/gene-protein/gene interaction network.
| Function | FDR | Genes in network |
|---|---|---|
| Regulation of protein kinase B signaling | 7.29E-13 | 10 |
| Protein kinase B signaling | 7.29E-13 | 10 |
| Phosphatidylinositol-mediated signaling | 1.12e-12 | 9 |
| Inositol lipid-mediated signaling | 6.57e-12 | 9 |
| Phosphatidylinositol 3-kinase signaling | 3.36e-09 | 7 |
| Regulation of phosphatidylinositol 3-kinase signaling | 7.63e-08 | 6 |
| Phosphatidylinositol metabolic process | 2.02666e-06 | 6 |
| Receptor tyrosine kinase binding | 5.74532e-05 | 3 |
| Phosphatidylinositol 3-kinase complex | 5.74532e-05 | 3 |