Fig. 3.
Increased availability of integrin β7 is insufficient to upregulate CD103 expression on Runx3Tg CD4 T cells. A Surface β7 expression on CD4 and CD8 LN T cells of WT and β7Tg mice. Data are representative (left), and bar graphs show the summary of 5 independent experiments (right) with a total of 5 WT and 5 β7Tg mice. B Surface CD103 expression on CD8 and CD4 LN T cells of WT and β7Tg mice. Data are representative, and bar graphs show the summary of 4 independent experiments with a total of 4 WT and 5 β7Tg mice (CD8) and 4 WT and 4 β7Tg mice (CD4). C Surface CD103 and β7 expression on CD4SP and CD8SP thymocytes (left) and CD4 and CD8 LN T cells (right) of Runx3Tgβ7Tg mice. The results are representative of 2 independent experiments with a total of 2 WT, 2 Runx3Tg and 2 Runx3Tgβ7Tg mice