Table 4.
Multivariate analysis of clinical factors with GBS colonization (vertical transmission) among neonates.
| Variables | Variable's categories | Frequency | GBS result | COR (95% CI) | P value | AOR (95% CI) | P value | |
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | |||||||
| Gravidity | Primigravida | 80 | 6 (7.5) | 74 (92.5) | 1.9 (0.55–6.39) | 0.311 | ||
| Multigravida | 121 | 5 (4.1) | 116 (95.9) | 1 | ||||
|
| ||||||||
| Parity | Nullipara | 25 | 5 (20.0) | 20 (80.0) | 6.2 (1.53–25.09) | 0.011 | 0.9 (0.10–8.42) | 0.938 |
| Primipara | 73 | 2 (2.7) | 71 (97.3) | 0.7 (0.12–3.91) | 0.682 | |||
| Multipara | 103 | 4 (3.9) | 99 (96.1) | 1 | ||||
|
| ||||||||
| Gestational age | <37 weeks | 10 | 5 (50) | 5 (50) | 30.8 (7.0–135.8) | ≤0.001 | 2.2 (1.9–5.4) | 0.008 |
| ≥37 weeks | 191 | 6 (3.1) | 185 (96.9) | 1 | ||||
|
| ||||||||
| Maternal UTI | Yes | 13 | 6 (40.0) | 9 (60.0) | 24.1 (6.2–94.3) | ≤0.001 | 3.6 (1.7–14.3) | 0.145 |
| No | 188 | 5 (2.7) | 181 (97.3) | 1 | ||||
|
| ||||||||
| History of PROM | Yes | 46 | 8 (17.4) | 38 (82.6) | 6.8 (1.89–24.32) | 0.003 | 5.07 (0.95–22.7) | 0.056 |
| No | 155 | 3 (1.9) | 152 (98.1) | 1 | ||||
|
| ||||||||
| Duration of PROM | <18 hours | 181 | 5 (2.8) | 176 (97.2) | 15.1 (4.1–55.7) | ≤0.001 | 3.28 (0.51–20.95) | 0.210 |
| >18 hours | 20 | 6 (30.0) | 14 (70.0) | 1 | ||||
|
| ||||||||
| Birth weight | <2.5 kg | 11 | 5 (45.5) | 6 (54.5) | 25.6 (6.1–107.7) | ≤0.001 | 2.5 (1.3–12.8) | 0.001 |
| ≥2.5 kg | 190 | 6 (3.2) | 184 (96.8) | 1 | ||||
|
| ||||||||
| Maternal fever | Yes | 18 | 2 (11.1) | 16 (88.9) | 2.42 (0.48–12.16) | 0.284 | ||
| No | 183 | 9 (4.9) | 174 (95.1) | 1 | ||||
|
| ||||||||
| Types of contraceptives used | Injectable | 48 | 3 (6.3) | 45 (93.7) | 0.85 (0.19–3.75) | 0.834 | ||
| Injection and pills | 41 | 1 (2.4) | 40 (97.6) | 0.32 (0.04–2.80) | 0.306 | |||
| Loop | 37 | 2 (5.4) | 35 (94.6) | 0.73 (0.14–3.97) | 0.717 | |||
| None | 69 | 5 (7.2) | 64 (92.8) | 1 | ||||
|
| ||||||||
| Number of ANC visit | 0–3 times | 63 | 2 (3.2) | 61 (96.8) | 0.47 (0.10–2.24) | 0.343 | ||
| 4-5 times | 138 | 9 (6.5) | 129 (93.5) | 1 | ||||
|
| ||||||||
| History of abortion | Yes | 27 | 2 (7.4) | 25 (92.6) | 1.47 (0.30–7.18) | 0.637 | ||
| No | 174 | 9 (5.2) | 165 (94.8) | 1 | ||||
|
| ||||||||
| Vaginal discharge | Yes | 13 | 6 (42.9) | 8 (57.1) | 27.3 (6.9–48.7) | ≤0.001 | 1.8 (2.6–6.6) | 0. 048 |
| No | 188 | 5 (2.7) | 182 (97.3) | 1 | ||||
AOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio; PROM, prolonged rupture of membranes; UTI, urinary tract infection; n, sample size.