Table 3.

Nucleic acid PROTACs targeting transcription factors (TF PROTACs).

Name	Target	POI ligand sequence	E3 ligase	Ref.
TRAFTACs	NF-κB brachyury	5′-GGGAATTTCC-3′ 5′-AATTTCACACCT-3′	VHL	108
TF-PROTACs	NF-κB E2F1	5′-GGGACTTTCC-3′ 5′-TTTCCCGCG-3′	VHL	107
O’PROTACs	LEF1 ERG	5′-AAAGATCAAAGGGTT-3′5′-GACCGGAAATCCGGTT-3′	VHL	109