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. 2021 Jun 30;9(5):1378–1388. doi: 10.1016/j.gendis.2021.06.002

Figure 1.

Fig. 1

Visualization of DEGs. (A, B) Volcano plot of DEGs. Green and red dots represent downregulated and upregulated genes respectively with the criterion of FC > 1.5 and padj<0.05. Blue dots are genes not meeting the inclusion criterion of DEG. (C, D) Hierarchical clustering heatmap of DEGs. The color of each grid represents the normalized value of gene expression, the redder the color, the higher the expression level; the bluer the color, the lower the expression level. HC (n = 7), Va (n = 7), Vt (n = 7). HC, healthy control. Va, VKH patients with active uveitis before treatment. Vt, VKH patients after the therapy of cyclosporine and prednisone. The same number after Va and Vt represents the same patient.